⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27754994 | 0.52 | — | — | |
| SCHEMBL2379897 | 0.51 | — | — | |
| SCHEMBL15427202 | 0.51 | — | — | |
| SCHEMBL10985274 | 0.48 | — | — | |
| SCHEMBL11570083 | 0.48 | — | — | |
| SCHEMBL10985271 | 0.48 | — | — | |
| SCHEMBL10985269 | 0.48 | — | — | |
| SCHEMBL11239093 | 0.47 | — | — | |
| SCHEMBL2207214 | 0.47 | — | — | |
| SCHEMBL1468768 | 0.43 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220055975-A1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | PTC THERAPEUTICS, INC. | 2022-02-24 | — | — | US | disclosed |
| US-11021424-B2 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | PTC THERAPEUTICS, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| EP-1933821-B1 | TAIL VARIANTS OF REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | PTC THERAPEUTICS INC (US) | 2020-07-29 | — | — | EP | disclosed |
| EP-2564843-B1 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | BIOELECTRON TECH CORP (US) | 2018-12-26 | — | — | EP | disclosed |
| EP-2471530-B1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | EDISON PHARMACEUTICALS INC (US) | 2017-01-11 | — | — | EP | disclosed |
| US-9447006-B2 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | EDISON PHARMACEUTICALS, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| EP-1888059-B1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | EDISON PHARMACEUTICALS INC (US) | 2014-12-17 | — | — | EP | disclosed |
| EP-2564842-A1 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | Edison Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2564843-A1 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | Edison Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2471530-A1 | Redox-active Therapeutics For Treatment Of Mitochondrial Diseases And Other Conditions And Modulation Of Energy Biomarkers | Edison Pharmaceuticals, Inc. (US) | 2012-07-04 | — | — | EP | disclosed |
| US-20100222436-A1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | PTC THERAPEUTICS, INC. | 2010-09-02 | — | — | US | disclosed |
| US-7432305-B2 | Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | EDISON PHARMACEUTICALS, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| EP-1933821-A1 | TAIL VARIANTS OF REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | Edison Pharmaceuticals, Inc. (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1888059-A2 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMAKERS | Edison Pharmaceuticals, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2007035496-A1 | TAIL VARIANTS OF REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | EDISON PHARMACEUTICALS, INC. (US) | 2007-03-29 | — | — | WO | disclosed |
| US-20070072943-A1 | Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | PTC THERAPEUTICS, INC. | 2007-03-29 | — | — | US | disclosed |
| US-20060281809-A1 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | PTC THERAPEUTICS, INC. | 2006-12-14 | — | — | US | disclosed |
| WO-2006130775-A2 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMAKERS | EDISON PHARMACEUTICALS, INC. (US) | 2006-12-07 | — | — | WO | disclosed |