Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 17/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.49 |
| ▸ | SPIN1 | Q9Y657 | 4/20 | 0.49 |
| ▸ | CHD1 | O14646 | 2/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20336907 | 1.00 | EHMT2 (0.49) | EHMT2DNMT1SPIN1CHD1EHMT1 | |
| SCHEMBL20336874 | 1.00 | EHMT2 (0.49) | EHMT2DNMT1SPIN1CHD1EHMT1 | |
| SCHEMBL30509152 | 1.00 | EHMT2 (0.49) | EHMT2DNMT1SPIN1CHD1EHMT1 | |
| SCHEMBL20336869 | 1.00 | EHMT2 (0.49) | EHMT2DNMT1SPIN1CHD1EHMT1 | |
| SCHEMBL20347668 | 0.91 | EHMT2 (0.42) | EHMT2DNMT1SPIN1CHD1EHMT1 | |
| SCHEMBL20347661 | 0.91 | EHMT2 (0.42) | EHMT2DNMT1SPIN1CHD1EHMT1 | |
| SCHEMBL20303984 | 0.88 | SPIN1 (0.55) | EHMT2DNMT1SPIN1CHD1EHMT1 | |
| SCHEMBL20347584 | 0.87 | SPIN1 (0.56) | EHMT2DNMT1SPIN1CHD1EHMT1 | |
| SCHEMBL20720629 | 0.86 | EHMT2 (0.68) | EHMT2 | |
| SCHEMBL19260715 | 0.86 | EHMT2 (0.68) | EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713299-B2 | Histone methyltransferase inhibitors | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713299-B2 | Histone methyltransferase inhibitors | EHMT1, DOT1L, EHMT2 | EHMT2 3/4885DNMT1 95/4885SPIN1 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.