Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 4/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | DUT | P33316 | 4/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16341309 | 0.83 | CYP3A4 (0.56) | CASRMTNR1AMTNR1BROCK2ROCK1 | |
| SCHEMBL16321584 | 0.83 | CYP3A4 (0.56) | CASRMTNR1AMTNR1BROCK2ROCK1 | |
| SCHEMBL16322842 | 0.73 | CYP3A4 (0.71) | CASRROCK2ROCK1MEN1KMT2A | |
| SCHEMBL16322840 | 0.73 | CYP3A4 (0.71) | CASRROCK2ROCK1MEN1KMT2A | |
| SCHEMBL16356132 | 0.73 | CYP3A4 (0.71) | CASRROCK2ROCK1MEN1KMT2A | |
| SCHEMBL16321591 | 0.70 | CYP3A4 (0.43) | CASRROCK2ROCK1MEN1KMT2A | |
| SCHEMBL16321590 | 0.70 | CYP3A4 (0.43) | CASRROCK2ROCK1MEN1KMT2A | |
| SCHEMBL19954204 | 0.66 | CASR (0.60) | CASRMEN1KMT2APOLB | |
| SCHEMBL16356126 | 0.66 | CYP3A4 (0.76) | MEN1KMT2ACYP3A4CYP2B6 | |
| SCHEMBL4926004 | 0.66 | CASR (0.49) | CASRROCK2ROCK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384729-B | Pyrimidinedione compounds for cardiac disorders | 迈奥卡迪亚公司 | 2023-06-30 | — | — | CN | disclosed |