Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DUT | P33316 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 3/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16322100 | 1.00 | CYP3A4 (0.46) | CYP3A4CYP2B6PGRSMN1; SMN2DUT | |
| SCHEMBL16322101 | 1.00 | CYP3A4 (0.46) | CYP3A4CYP2B6PGRSMN1; SMN2DUT | |
| SCHEMBL16321660 | 0.89 | CYP3A4 (0.48) | CYP3A4CYP2B6PGRSMN1; SMN2HTT | |
| SCHEMBL16321659 | 0.89 | CYP3A4 (0.48) | CYP3A4CYP2B6PGRSMN1; SMN2HTT | |
| SCHEMBL16321187 | 0.87 | CYP3A4 (0.56) | CYP3A4CYP2B6PGRSMN1; SMN2EGFR | |
| SCHEMBL16321188 | 0.87 | CYP3A4 (0.56) | CYP3A4CYP2B6PGRSMN1; SMN2EGFR | |
| SCHEMBL16321590 | 0.86 | CYP3A4 (0.43) | CYP3A4CYP2B6SMN1; SMN2IDH1POLB | |
| SCHEMBL16321591 | 0.86 | CYP3A4 (0.43) | CYP3A4CYP2B6SMN1; SMN2IDH1POLB | |
| SCHEMBL16321751 | 0.79 | CYP3A4 (0.74) | CYP3A4CYP2B6PGRSMN1; SMN2DUT | |
| SCHEMBL31686185 | 0.79 | CYP3A4 (0.74) | CYP3A4CYP2B6PGRSMN1; SMN2DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384729-B | Pyrimidinedione compounds for cardiac disorders | 迈奥卡迪亚公司 | 2023-06-30 | — | — | CN | disclosed |