(Z)-Aurone

(Z)-Aurone

SCHEMBL305100

O=C1/C(=C/c2ccccc2)Oc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK17B O94768 6/20 1.00
MAOA P21397 3/20 0.76
MAOB P27338 3/20 0.76
HDAC3 O15379 2/20 0.76
HDAC4 P56524 2/20 0.76
HDAC1 Q13547 2/20 0.76
HDAC7 Q8WUI4 2/20 0.76
HDAC2 Q92769 2/20 0.76
HDAC10 Q969S8 2/20 0.76
HDAC11 Q96DB2 2/20 0.76
HDAC8 Q9BY41 2/20 0.76
HDAC6 Q9UBN7 2/20 0.76
HDAC9 Q9UKV0 2/20 0.76
HDAC5 Q9UQL6 2/20 0.76
ELANE P08246 6/20 0.74
ACHE P22303 3/20 0.69
CISD1 Q9NZ45 1/20 0.69
MEN1 O00255 1/20 0.65
RECQL P46063 1/20 0.65
KMT2A Q03164 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-Aurone SCHEMBL305101 1.00 STK17B (1.00) STK17BMAOAMAOBHDAC3HDAC4
(Z)-Aurone SCHEMBL31266594 1.00 STK17B (1.00) STK17BMAOAMAOBHDAC3HDAC4
(Z)-Aurone SCHEMBL13971324 1.00 STK17B (1.00) STK17BMAOAMAOBHDAC3HDAC4
(Z)-Aurone SCHEMBL29935711 1.00 STK17B (1.00) STK17BMAOAMAOBHDAC3HDAC4
SCHEMBL19499394 0.94 STK17B (0.89) STK17BMAOAMAOBHDAC3HDAC4
SCHEMBL19462733 0.94 STK17B (0.89) STK17BMAOAMAOBHDAC3HDAC4
SCHEMBL19499403 0.90 STK17B (0.81) STK17BMAOAMAOBHDAC3HDAC4
SCHEMBL21082587 0.86 STK17B (0.76) STK17BMAOAMAOBHDAC3HDAC4
SCHEMBL21046410 0.86 STK17B (0.76) STK17BMAOAMAOBHDAC3HDAC4
SCHEMBL19462898 0.86 MAOA (1.00) STK17BMAOAMAOBHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059625-A Mineral wool binder 洛科威有限公司 2026-05-19 CN claimed
US-12614680-B1 Dye-sensitized solar cell based on titanium dioxide, graphitic carbon nitride, and cadmium selenide nanocomposite KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-04-28 US claimed
EP-4580612-A1 USE OF NRF2 ACTIVATORS FOR THE TREATMENT OF CEREBRAL SMALL VESSEL DISEASE Institut National de la Santé et de la Recherche Médicale (FR) 2025-07-09 EP claimed
CN-119462619-A Orange ketone compound and medical application thereof 浙江大学 2025-02-18 CN claimed
EP-4013725-B1 MINERAL WOOL BINDER ROCKWOOL AS (DK) 2024-10-02 EP claimed
US-20240316118-A1 ANTIVIRAL NASAL SPRAY FLAVONOIDS?BEE PROPOLIS MCCAFFREY STEPHEN MARK (AU) 2024-09-26 US claimed
CN-118356425-A Semisynthetic aurone and its use method 肯塔基大学研究基金会 2024-07-19 CN claimed
CN-118356427-A Semisynthetic aurone and its use method 肯塔基大学研究基金会 2024-07-19 CN claimed
CN-118063419-A Orange ketoxime ester photoinitiator, preparation method and application thereof 大连理工大学 2024-05-24 CN claimed
CN-116270345-B Natural herbal cosmetic with effects of radiation protection, blood circulation activating, skin nourishing and anti-aging and application thereof 北京娅熙妍国际贸易有限公司 2024-04-26 CN claimed
CN-1272140-A Gene encoding protein having aurone synthesizing activity SUNTORY LTD (JP) 2000-11-01 CN claimed
EP-1001028-A1 GENE ENCODING PROTEIN HAVING AURONE SYNTHESIZING ACTIVITY SUNTORY LIMITED (JP) 2000-05-17 EP claimed
WO-1997026873-A1 ANTIMICROBIAL AURONE DERIVATIVES PHYTERA, INC. (US) 1997-07-31 WO claimed
US-5603936-A SOLVENT EXTRACTION Ratcliff, Richard A. (US) 1997-02-18 US claimed
EP-0528975-A4 GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES 1993-09-15 EP claimed
EP-0528975-A1 GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES BAYLOR COLLEGE OF MEDICINE (US) 1993-03-03 EP claimed
WO-1993001824-A1 COMBINATION THERAPY USING BIOFLAVONOID COMPOUNDS WITH ANTI-CANCER DRUGS BAYLOR COLLEGE OF MEDICINE (US) 1993-02-04 WO claimed
WO-1991017749-A1 GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES BAYLOR COLLEGE OF MEDICINE (US) 1991-11-28 WO claimed
US-RE32196-E PROPHYLACTIC CHEMOTHERAPY OF ALLERGIC CONDITIONS LILLY INDUSTRIES LIMITED (GB) 1986-07-01 US claimed
US-4259340-A PROPHYLACTIC CHEMOTHERAPY OF ALLERGIC CONDITIONS SUCH AS ASTHMA LILLY INDUSTRIES LIMITED (GB) 1981-03-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12614680-B1 Dye-sensitized solar cell based on titanium dioxide, graphitic carbon nitride, and cadmium selenide nanocomposite SCN9A, CD2, CA9 STK17B 2248/4885MAOA 2958/4885MAOB 2622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.