Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 10/20 | 0.63 |
| ▸ | MC1R | Q01726 | 9/20 | 0.63 |
| ▸ | MC5R | P33032 | 8/20 | 0.63 |
| ▸ | MC3R | P41968 | 8/20 | 0.63 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.54 |
| ▸ | TUBB | P07437 | 2/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.54 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29476567 | 1.00 | MC4R (0.63) | MC4RMC1RMC5RMC3RTUBB4A | |
| SCHEMBL29476581 | 1.00 | MC4R (0.63) | MC4RMC1RMC5RMC3RTUBB4A | |
| SCHEMBL29511302 | 0.97 | MC4R (0.65) | MC4RMC1RMC5RMC3RTUBB4A | |
| SCHEMBL31140226 | 0.97 | MC4R (0.65) | MC4RMC1RMC5RMC3RTUBB4A | |
| SCHEMBL29482482 | 0.97 | MC4R (0.67) | MC4RMC1RMC5RMC3RTUBB4A | |
| SCHEMBL29482492 | 0.97 | MC4R (0.67) | MC4RMC1RMC5RMC3RTUBB4A | |
| SCHEMBL29476424 | 0.97 | MC4R (0.67) | MC4RMC1RMC5RMC3RTUBB4A | |
| SCHEMBL29476538 | 0.97 | MC4R (0.67) | MC4RMC1RMC5RMC3RTUBB4A | |
| SCHEMBL29510982 | 0.97 | MC4R (0.67) | MC4RMC1RMC5RMC3RTUBB4A | |
| SCHEMBL29510995 | 0.97 | MC4R (0.67) | MC4RMC1RMC5RMC3RTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507353-A | Methods of treating melanocortin-4 receptor pathway-related disorders | 节奏制药公司 | 2023-07-28 | — | — | CN | disclosed |