Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 4/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSH | P09668 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30510368 | 0.96 | NPY4R (0.44) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29511079 | 0.94 | NPY4R (0.44) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29476385 | 0.94 | NPY4R (0.43) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30510278 | 0.93 | NPY4R (0.44) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30510326 | 0.92 | MC4R (0.51) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30044979 | 0.90 | NPY4R (0.42) | MC4RNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL30028749 | 0.89 | FOLH1 (0.44) | MC4RNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL31555124 | 0.89 | MC4R (0.54) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31555118 | 0.89 | MC4R (0.54) | MC4RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31555119 | 0.89 | MC4R (0.54) | MC4RTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507353-A | Methods of treating melanocortin-4 receptor pathway-related disorders | 节奏制药公司 | 2023-07-28 | — | — | CN | disclosed |