Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 5/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | BPTF | Q12830 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP4 | P49662 | 1/20 | 0.35 |
| ▸ | CASP5 | P51878 | 1/20 | 0.35 |
| ▸ | GALR2 | O43603 | 2/20 | 0.35 |
| ▸ | GALR1 | P47211 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25386786 | 1.00 | AURKA (0.40) | AURKAROCK2BPTFROCK1RIPK1 | |
| SCHEMBL25386533 | 0.86 | BPTF (0.55) | AURKAROCK2BPTFROCK1RIPK1 | |
| SCHEMBL30514109 | 0.84 | KCNH2 (0.48) | AURKAKCNH2AURKBGALR2GALR1 | |
| SCHEMBL25385598 | 0.84 | KCNH2 (0.48) | AURKAKCNH2AURKBGALR2GALR1 | |
| SCHEMBL30514112 | 0.84 | KCNH2 (0.42) | AURKAROCK2BPTFROCK1RIPK1 | |
| SCHEMBL30514104 | 0.84 | KCNH2 (0.56) | AURKAROCK2BPTFRIPK1KCNH2 | |
| SCHEMBL25387093 | 0.84 | KCNH2 (0.56) | AURKAROCK2BPTFRIPK1KCNH2 | |
| SCHEMBL25386410 | 0.84 | KCNH2 (0.42) | AURKAROCK2BPTFROCK1RIPK1 | |
| SCHEMBL30661962 | 0.80 | KCNH2 (0.46) | BPTFROCK1KCNH2 | |
| SCHEMBL25386721 | 0.79 | GALR2 (0.52) | GALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242203-A1 | NOVEL CAPSID ASSEMBLY INHIBITOR | Pelemed Co., Ltd. (KR) | 2023-09-13 | — | — | EP | disclosed |
| CN-116507611-A | Novel capsid assembly inhibitor | 佩勒梅德有限公司 | 2023-07-28 | — | — | CN | disclosed |