Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.72 |
| ▸ | DRD1 | P21728 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29783561 | 1.00 | PRCP (0.72) | PRCPDRD1DRD2HDAC3HDAC1 | |
| SCHEMBL28759510 | 1.00 | PRCP (0.72) | PRCPDRD1DRD2HDAC3HDAC1 | |
| SCHEMBL8415128 | 0.84 | PRCP (1.00) | PRCPDRD1DRD2HDAC3HDAC1 | |
| SCHEMBL13928812 | 0.84 | PRCP (1.00) | PRCPDRD1DRD2HDAC3HDAC1 | |
| SCHEMBL25604565 | 0.84 | PRCP (1.00) | PRCPDRD1DRD2HDAC3HDAC1 | |
| Iodide SCHEMBL27518895 | 0.83 | PRCP (0.97) | PRCPDRD1DRD2HDAC3HDAC1 | |
| SCHEMBL30297009 | 0.82 | ESR1 (0.60) | PRCPDRD1 | |
| SCHEMBL29170183 | 0.82 | ESR1 (0.60) | PRCPDRD1 | |
| SCHEMBL14417376 | 0.82 | PRCP (0.74) | PRCPDRD1DRD2HDAC3HDAC1 | |
| SCHEMBL7585517 | 0.81 | PRCP (0.65) | PRCPDRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516835-B | Synthesis method of alpha, alpha-disubstituted tetrahydroisoquinoline compound | 西安石油大学 | 2023-08-15 | — | — | CN | disclosed |