Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 13/20 | 0.73 |
| ▸ | FGFR4 | P22455 | 10/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29063917 | 1.00 | FGFR2 (0.73) | FGFR2FGFR4FGFR1KDRFGFR3 | |
| SCHEMBL29063914 | 1.00 | FGFR2 (0.73) | FGFR2FGFR4FGFR1KDRFGFR3 | |
| SCHEMBL29064195 | 0.92 | FGFR2 (0.74) | FGFR2FGFR4FGFR1KDRFGFR3 | |
| SCHEMBL29064198 | 0.92 | FGFR2 (0.74) | FGFR2FGFR4FGFR1KDRFGFR3 | |
| SCHEMBL30516043 | 0.92 | FGFR2 (0.74) | FGFR2FGFR4FGFR1KDRFGFR3 | |
| SCHEMBL29064418 | 0.85 | FGFR2 (0.84) | FGFR2FGFR4FGFR1KDRFGFR3 | |
| SCHEMBL29064425 | 0.85 | FGFR2 (0.84) | FGFR2FGFR4FGFR1KDRFGFR3 | |
| SCHEMBL30515903 | 0.85 | FGFR2 (0.84) | FGFR2FGFR4FGFR1KDRFGFR3 | |
| SCHEMBL29063646 | 0.84 | BTK (0.54) | FGFR2FGFR4FGFR1KDRFGFR3 | |
| SCHEMBL29063643 | 0.84 | BTK (0.54) | FGFR2FGFR4FGFR1KDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514806-A | Biological inhibitor containing acrylketone, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |