Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248663 | 1.00 | HDAC6 (0.63) | HDAC6PRSS1PTGER4KAT2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL4862759 | 0.98 | HDAC6 (0.61) | HDAC6PRSS1PTGER4KAT2BALDH1A1 | |
| SCHEMBL6253238 | 0.95 | HDAC6 (0.61) | HDAC6PRSS1PTGER4KAT2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL4864775 | 0.93 | HDAC6 (0.60) | HDAC6PRSS1PTGER4KAT2BALDH1A1 | |
| SCHEMBL1497919 | 0.89 | HDAC6 (0.58) | HDAC6PRSS1PTGER4ALDH1A1HSD17B10 | |
| SCHEMBL124591 | 0.89 | HDAC6 (0.71) | HDAC6PRSS1PTGER4KAT2BALDH1A1 | |
| SCHEMBL7137884 | 0.84 | HDAC6 (0.65) | HDAC6PRSS1KAT2BALOX15TP53 | |
| SCHEMBL5806008 | 0.83 | HDAC6 (0.63) | HDAC6PRSS1KAT2B | |
| SCHEMBL14906563 | 0.83 | HDAC6 (0.63) | HDAC6PRSS1PTGER4KAT2BALDH1A1 | |
| SCHEMBL21016436 | 0.81 | HDAC6 (0.61) | HDAC6PRSS1PTGER4KAT2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528867-A | Compounds for the treatment of Alzheimer's disease | 艾伯塔大学理事会 | 2023-08-01 | — | — | CN | disclosed |