Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13363888 | 1.00 | CYP19A1 (0.51) | CYP19A1CYP11B1CYP11B2SLC2A1NAMPT | |
| SCHEMBL5293345 | 0.85 | SMN1; SMN2 (0.63) | ALDH1A1CYP2C19SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2114045 | 0.85 | SMN1; SMN2 (0.54) | NAMPTALDH1A1CYP2C9CYP2C19CYP2E1 | |
| SCHEMBL13363878 | 0.84 | CYP46A1 (0.49) | ALDH1A1CYP2C19USP30SMN1; SMN2RAB9A | |
| SCHEMBL23930645 | 0.84 | CYP2A6 (0.54) | NAMPTCYP2C9CYP2C19CYP2E1CYP2A6 | |
| SCHEMBL30516614 | 0.82 | CYP2E1 (0.55) | CYP19A1NAMPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL370074 | 0.82 | CYP2E1 (0.55) | CYP19A1NAMPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL30516607 | 0.81 | CYP2E1 (0.57) | NAMPTCYP2C9CYP2C19CYP2E1CYP2A6 | |
| SCHEMBL6872027 | 0.81 | CYP2E1 (0.57) | NAMPTCYP2C9CYP2C19CYP2E1CYP2A6 | |
| SCHEMBL368446 | 0.81 | CYP2C9 (0.54) | CYP19A1NAMPTALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528862-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-08-01 | — | — | CN | disclosed |