⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790344 | 0.72 | — | — | |
| SCHEMBL2339270 | 0.72 | — | — | |
| SCHEMBL19838028 | 0.67 | — | — | |
| SCHEMBL6135306 | 0.67 | — | — | |
| SCHEMBL8802624 | 0.67 | — | — | |
| SCHEMBL1756627 | 0.64 | — | — | |
| SCHEMBL184294 | 0.62 | — | — | |
| SCHEMBL148135 | 0.62 | — | — | |
| SCHEMBL108578 | 0.62 | — | — | |
| SCHEMBL1727714 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060111274-A1 | Methods and compositions for enhancing transport across biological membranes | THE BOARD OF TRUSTEES OF THE LELAND STANFORD (US) | 2006-05-25 | — | — | US | claimed |
| EP-0975370-B9 | COMPOSITION AND METHOD FOR ENHANCING TRANSPORT ACROSS BIOLOGICAL MEMBRANES | UNIV LELAND STANFORD JUNIOR (US) | 2004-11-03 | — | — | EP | claimed |
| EP-0975370-B1 | COMPOSITION AND METHOD FOR ENHANCING TRANSPORT ACROSS BIOLOGICAL MEMBRANES | UNIV LELAND STANFORD JUNIOR (US) | 2003-10-15 | — | — | EP | claimed |
| US-20030162719-A1 | Method and composition for enhancing transport across biological membranes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-08-28 | — | — | US | claimed |
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | claimed |
| US-20240216486-A1 | INJECTABLE BOTULINUM TOXIN METHODS FOR TREATING HEADACHES | REVANCE THERAPEUTICS, INC. | 2024-07-04 | — | — | US | disclosed |
| US-11911449-B2 | Albumin-free botulinum toxin formulations | REVANCE THERAPEUTICS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20240058628-A1 | INJECTABLE BOTULINUM TOXIN FORMULATIONS | JPMORGAN CHASE BANK, N.A. | 2024-02-22 | — | — | US | disclosed |
| CN-117279654-A | Method for treating cervical dystonia | 雷文斯治疗公司 | 2023-12-22 | — | — | CN | disclosed |
| US-20230210963-A1 | INJECTABLE BOTULINUM TOXIN METHOS FOR TREATING HEADACHES | REVANCE THERAPEUTICS, INC. | 2023-07-06 | — | — | US | disclosed |
| EP-4121169-A2 | INJECTABLE BOTULINUM TOXIN METHODS FOR TREATING HEADACHES | ReVance Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| US-20220347275-A1 | Methods and Compositions for Treating Skin Conditions Associated With Vascular Hyper-reactivity | REVANCE THERAPEUTICS, INC. (US) | 2022-11-03 | — | — | US | disclosed |
| US-6306406-B1 | FOR CONTOLLED RELEASE OF CALCITONIN | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2001-10-23 | — | — | US | disclosed |
| WO-2001062297-A1 | COMPOSITIONS AND METHODS FOR ENHANCING DRUG DELIVERY ACROSS BIOLOGICAL MEMBRANES AND TISSUES | CELLGATE, INC. (US) | 2001-08-30 | — | — | WO | disclosed |
| WO-2001013957-A2 | ENHANCING DRUG DELIVERY ACROSS AND INTO EPITHELIAL TISSUES USING OLIGO ARGININE MOIETIES | CELLGATE, INC. (US) | 2001-03-01 | — | — | WO | disclosed |
| EP-0975370-A2 | COMPOSITION AND METHOD FOR ENHANCING TRANSPORT ACROSS BIOLOGICAL MEMBRANES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0467389-B1 | Drug delivery system comprising interaction between calcitonin and a hydrophobic biodegradable polymer | UNIV KENTUCKY RES FOUND (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998052614-A2 | COMPOSITION AND METHOD FOR ENHANCING TRANSPORT ACROSS BIOLOGICAL MEMBRANES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1998-11-26 | — | — | WO | disclosed |
| EP-0467389-A2 | Drug delivery system involving interaction between protein or polypeptide and hydrophobic biodegradable polymer | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1992-01-22 | — | — | EP | disclosed |
| US-4897444-A | Immobilized fluorogenic substrates for enzymes; and processes for their preparation | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 1990-01-30 | — | — | US | disclosed |