Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 20/20 | 0.67 |
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22769812 | 1.00 | PDCD1 (0.67) | PDCD1CD274 | |
| SCHEMBL24446140 | 0.96 | PDCD1 (0.64) | PDCD1CD274 | |
| SCHEMBL22675462 | 0.94 | PDCD1 (0.61) | PDCD1CD274 | |
| SCHEMBL24446142 | 0.91 | PDCD1 (0.58) | PDCD1CD274 | |
| SCHEMBL24446650 | 0.91 | PDCD1 (0.73) | PDCD1CD274 | |
| SCHEMBL24446157 | 0.86 | PDCD1 (0.57) | PDCD1CD274 | |
| SCHEMBL28783906 | 0.85 | PDCD1 (0.53) | PDCD1CD274 | |
| SCHEMBL30112620 | 0.83 | PDCD1 (0.64) | PDCD1CD274 | |
| SCHEMBL22769791 | 0.83 | PDCD1 (0.64) | PDCD1CD274 | |
| SCHEMBL22769830 | 0.83 | PDCD1 (0.78) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3750887-B1 | BIARYL DERIVATIVES AND THEIR PHARMACEUTICAL APPLICATION FOR THE TREATMENT OF PD-1/PD-L1 SIGNAL PATHWAY-MEDIATED DISEASES | ABBISKO THERAPEUTICS CO LTD (CN) | 2025-05-28 | — | — | EP | disclosed |
| WO-2023169373-A1 | HOLOSYMMETRIC BIPHENYL DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2023-09-14 | — | — | WO | disclosed |