Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 6/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.64 |
| ▸ | KDR | P35968 | 5/20 | 0.64 |
| ▸ | LCK | P06239 | 3/20 | 0.64 |
| ▸ | SRC | P12931 | 2/20 | 0.64 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.63 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.63 |
| ▸ | CSF1R | P07333 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933740 | 1.00 | MAPT (0.68) | MAPTHTTMEN1RAB9AKMT2A | |
| SCHEMBL2497760 | 0.90 | MEN1 (0.68) | MAPTHTTMEN1RAB9AKMT2A | |
| SCHEMBL12858514 | 0.88 | MAPT (0.74) | MAPTHTTMEN1RAB9AKMT2A | |
| SCHEMBL2970952 | 0.86 | MAPT (0.70) | MAPTHTTMEN1RAB9AKMT2A | |
| SCHEMBL1264375 | 0.86 | MAPT (0.74) | MAPTHTTMEN1RAB9AKMT2A | |
| SCHEMBL20467572 | 0.86 | MAPT (0.70) | MAPTHTTMEN1RAB9AKMT2A | |
| SCHEMBL2313285 | 0.85 | MAPT (0.68) | MAPTHTTMEN1RAB9AKMT2A | |
| SCHEMBL16121292 | 0.85 | MAPT (0.68) | MAPTHTTMEN1RAB9AKMT2A | |
| SCHEMBL2975743 | 0.85 | MAPT (0.68) | MAPTHTTMEN1RAB9AKMT2A | |
| SCHEMBL29561542 | 0.85 | MAPT (0.68) | MAPTHTTMEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761801-A | Heterocyclic compounds having protein kinase inhibitory activity, pharmaceutical compositions containing the same, and methods of preparing and using the same | 四川科伦博泰生物医药股份有限公司 | 2023-09-15 | — | — | CN | disclosed |