Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 3/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16145860 | 1.00 | MAPT (0.51) | MAPTHTR2BTMIGD3HTR2CPRMT1 | |
| SCHEMBL16145780 | 0.88 | HTR2B (0.52) | MAPTHTR2BTMIGD3HTR2CPRMT1 | |
| SCHEMBL30523360 | 0.88 | HTR2B (0.52) | MAPTHTR2BTMIGD3HTR2CPRMT1 | |
| SCHEMBL16146391 | 0.86 | MAPT (0.57) | MAPTHTR2BTMIGD3HTR2CPRMT1 | |
| SCHEMBL30523413 | 0.85 | CDK1 (0.67) | MAPTHTR2BTMIGD3HTR2CCDK1 | |
| SCHEMBL16145984 | 0.85 | CDK1 (0.67) | MAPTHTR2BTMIGD3HTR2CCDK1 | |
| SCHEMBL16147024 | 0.83 | PRMT1 (0.69) | MAPTHTR2BTMIGD3HTR2CPRMT1 | |
| SCHEMBL16145956 | 0.81 | STAT3 (0.64) | MAPTHTR2BTMIGD3HTR2CPRMT1 | |
| SCHEMBL16145859 | 0.81 | ALPG (0.50) | MAPTPRMT1ALPLALPGPLAA | |
| SCHEMBL16146206 | 0.81 | MAPT (0.57) | MAPTHTR2BTMIGD3HTR2CPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116492347-A | Compound for activating AMPK and application thereof | 华安医学股份有限公司 | 2023-07-28 | — | — | CN | disclosed |