SCHEMBL30523621

SCHEMBL30523621

COc1cc(OC(C)C)ccc1CNC(=O)N(Cc1ccc(F)cc1F)C1CCN(C)CC1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20766383 1.00 HTR2A (0.65) HTR2A
SCHEMBL22374103 0.93 HTR2A (0.63) HTR2A
SCHEMBL20766348 0.92 HTR2A (0.70) HTR2A
SCHEMBL30523679 0.90 HTR2A (0.67) HTR2A
SCHEMBL20766231 0.90 HTR2A (0.67) HTR2A
SCHEMBL22361719 0.89 HTR2A (0.76) HTR2A
SCHEMBL30523478 0.89 HTR2A (0.76) HTR2A
SCHEMBL30523644 0.86 HTR2A (0.72) HTR2A
SCHEMBL20766323 0.86 HTR2A (0.72) HTR2A
SCHEMBL22361706 0.85 HTR2A (0.65) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4635568-A2 COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES ACADIA Pharmaceuticals Inc. (US) 2025-10-22 — — EP disclosed
EP-3672954-B1 COMPOUNDS, SALTS THEREOF AND THEIR USE FOR THE TREATMENT OF DISEASES ACADIA PHARM INC (US) 2025-08-13 — — EP disclosed
CN-117466803-A Compounds, salts thereof and methods for treating diseases 阿卡蒂亚药品公司 2024-01-30 — — CN disclosed
CN-111132976-B Compounds, salts thereof and methods for treating diseases 阿卡蒂亚药品公司 2023-08-22 — — CN disclosed
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