Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22361712 | 1.00 | KDM1A (0.53) | KDM1AMAOAMAOBHTTALDH1A1 | |
| SCHEMBL25683679 | 0.89 | KDM1A (0.60) | KDM1AMAOAMAOBHTTALDH1A1 | |
| SCHEMBL25683528 | 0.86 | KDM1A (0.57) | KDM1AMAOAMAOBHTTALDH1A1 | |
| SCHEMBL4733093 | 0.85 | TSHR (0.57) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL22361693 | 0.85 | EPHX2 (0.55) | HTTALDH1A1KDM4E | |
| SCHEMBL30523692 | 0.84 | BCHE (0.48) | HTTALDH1A1KDM4EBCHEACHE | |
| SCHEMBL22361727 | 0.84 | BCHE (0.48) | HTTALDH1A1KDM4EBCHEACHE | |
| SCHEMBL20766753 | 0.83 | BCHE (0.64) | HTTALDH1A1KDM4ECXCR3BCHE | |
| SCHEMBL29546328 | 0.83 | BCHE (0.64) | HTTALDH1A1KDM4ECXCR3BCHE | |
| SCHEMBL12074147 | 0.82 | BCHE (0.50) | HTTALDH1A1KDM4ECXCR3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466803-A | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-111132976-B | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2023-08-22 | — | — | CN | disclosed |