Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.73 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | DRD1 | P21728 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.73 |
| ▸ | GPR183 | P32249 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.73 |
| ▸ | APLNR | P35414 | 1/20 | 0.73 |
| ▸ | DRD3 | P35462 | 1/20 | 0.73 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.73 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766932 | 1.00 | HTR2A (0.79) | HTR2AABCB11CYP1A2ADRB2CHRM2 | |
| SCHEMBL20778700 | 0.91 | HTR2A (0.77) | HTR2AABCB11CYP1A2ADRB2CHRM2 | |
| SCHEMBL20766380 | 0.90 | HTR2A (0.75) | HTR2AABCB11CYP1A2ADRB2CHRM2 | |
| SCHEMBL20766308 | 0.90 | HTR2A (0.75) | HTR2AABCB11CYP1A2ADRB2CHRM2 | |
| SCHEMBL30523652 | 0.90 | HTR2A (0.75) | HTR2AABCB11CYP1A2ADRB2CHRM2 | |
| SCHEMBL22374156 | 0.90 | HTR2A (0.77) | HTR2AABCB11CYP1A2ADRB2CHRM2 | |
| SCHEMBL20766372 | 0.89 | HTR2A (0.81) | HTR2AABCB11CYP1A2ADRB2CHRM2 | |
| SCHEMBL30523480 | 0.89 | HTR2A (0.81) | HTR2AABCB11CYP1A2ADRB2CHRM2 | |
| SCHEMBL20766360 | 0.89 | HTR2A (0.81) | HTR2AABCB11CYP1A2ADRB2CHRM2 | |
| SCHEMBL20766824 | 0.88 | HTR2A (1.00) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466803-A | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-111132976-B | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2023-08-22 | — | — | CN | disclosed |