Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.77 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30376062 | 1.00 | NR1H2 (0.77) | NR1H2JAK1JAK2NAMPTUSP2 | |
| SCHEMBL25025541 | 1.00 | NR1H2 (0.77) | NR1H2JAK1JAK2NAMPTUSP2 | |
| Hydrochloric Acid SCHEMBL25258353 | 0.91 | NR1H2 (0.64) | NR1H2JAK1JAK2NAMPTEPHX2 | |
| SCHEMBL25025883 | 0.88 | NR1H2 (0.72) | NR1H2JAK1JAK2NAMPTUSP2 | |
| SCHEMBL2993190 | 0.87 | NR1H2 (1.00) | NR1H2JAK1JAK2NAMPTUSP2 | |
| SCHEMBL20936805 | 0.87 | NR1H2 (1.00) | NR1H2JAK1JAK2NAMPTUSP2 | |
| SCHEMBL23406722 | 0.87 | NR1H2 (1.00) | NR1H2JAK1JAK2NAMPTUSP2 | |
| SCHEMBL372106 | 0.87 | NR1H2 (1.00) | NR1H2JAK1JAK2NAMPTUSP2 | |
| SCHEMBL903882 | 0.87 | NR1H2 (1.00) | NR1H2JAK1JAK2NAMPTUSP2 | |
| SCHEMBL20031473 | 0.87 | NR1H2 (1.00) | NR1H2JAK1JAK2NAMPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118613473-A | Compounds and compositions for treating disorders associated with STING activity | 艾福姆德尤股份有限公司 | 2024-09-06 | — | — | CN | disclosed |
| US-20230250060-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250060-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | NR1H2 972/4885JAK1 393/4885JAK2 501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.