Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541012 | 0.89 | MC4R (0.49) | MC4R | |
| SCHEMBL21540634 | 0.89 | MC4R (0.49) | MC4R | |
| SCHEMBL30524906 | 0.87 | KCNH2 (0.51) | KCNH2MC4RP2RX7HTR2CMTOR | |
| SCHEMBL20811542 | 0.87 | KCNH2 (0.51) | KCNH2MC4RP2RX7HTR2CMTOR | |
| Trifluoroacetic Acid SCHEMBL22206760 | 0.83 | MC4R (0.49) | KCNH2MC4RP2RX7HTR2CMAOA | |
| SCHEMBL16347630 | 0.83 | MEN1 (0.49) | MC4RHTR2CMAPT | |
| SCHEMBL18319244 | 0.83 | MEN1 (0.49) | MC4RHTR2CMAPT | |
| SCHEMBL1162854 | 0.82 | MC4R (0.59) | MC4RHTR2C | |
| SCHEMBL15646384 | 0.82 | NAMPT (0.51) | MAPTF2 | |
| Hydrochloric Acid SCHEMBL23321183 | 0.82 | MEN1 (0.47) | MC4RHTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601798-B | Bisamide sarcomere activating compounds and uses thereof | 美国安进公司 | 2023-08-11 | — | — | CN | claimed |
| CN-111601798-B | Bisamide sarcomere activating compounds and uses thereof | 美国安进公司 | 2023-08-11 | — | — | CN | disclosed |