Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLK1 | O15075 | 7/20 | 0.52 |
| ▸ | MAPK7 | Q13164 | 8/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.46 |
| ▸ | AURKA | O14965 | 3/20 | 0.46 |
| ▸ | PIK3C2G | O75747 | 3/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 7/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.36 |
| ▸ | DCLK2 | Q8N568 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25357908 | 1.00 | DCLK1 (0.52) | DCLK1MAPK7LRRK2PIK3CDAURKA | |
| SCHEMBL10098691 | 0.84 | MAPK7 (0.56) | DCLK1MAPK7LRRK2PIK3CDAURKA | |
| SCHEMBL29582820 | 0.80 | DCLK1 (0.48) | DCLK1MAPK7LRRK2PIK3CDAURKA | |
| SCHEMBL17059738 | 0.79 | DCLK1 (0.45) | DCLK1MAPK7LRRK2PIK3CDAURKA | |
| SCHEMBL23144761 | 0.75 | MAPK7 (0.53) | DCLK1MAPK7LRRK2PIK3CDAURKA | |
| SCHEMBL16065726 | 0.75 | MAPK7 (0.54) | DCLK1MAPK7LRRK2PIK3CDAURKA | |
| SCHEMBL20094145 | 0.72 | LRRK2 (0.50) | DCLK1MAPK7LRRK2PIK3CDAURKA | |
| SCHEMBL20094162 | 0.72 | MAPK7 (0.51) | DCLK1MAPK7LRRK2PIK3CDAURKA | |
| SCHEMBL10098766 | 0.71 | DCLK1 (0.58) | DCLK1MAPK7LRRK2PIK3CDAURKA | |
| SCHEMBL16065742 | 0.71 | MAPK7 (0.45) | DCLK1MAPK7LRRK2PIK3CDAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479400-A1 | HETEROCYCLIC COMPOUNDS USEFUL FOR TREATING A ERK5-MEDIATED DISEASE | Cancer Research Technology Limited (GB) | 2024-12-25 | — | — | EP | disclosed |
| CN-119053604-A | Heterocyclic compounds for the treatment of ERK5 mediated diseases | 癌症研究技术有限公司 | 2024-11-29 | — | — | CN | disclosed |
| WO-2023156791-A1 | HETEROCYCLIC COMPOUNDS USEFUL FOR TREATING A ERK5-MEDIATED DISEASE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-08-24 | — | — | WO | disclosed |