Bromide

Bromide

SCHEMBL30526367

CCCC[n+]1ccccc1C.[Br-]

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 11/20 0.41
CHRM2 known ✓ P08172 1/20 0.39
CHRM4 known ✓ P08173 1/20 0.39
CHRM5 known ✓ P08912 1/20 0.39
CHRM1 known ✓ P11229 1/20 0.39
CHRM3 known ✓ P20309 1/20 0.39
SMN1; SMN2 Q16637 7/20 0.78
NPC1 O15118 6/20 0.78
RAB9A P51151 6/20 0.78
POLB P06746 1/20 0.78
HTT P42858 6/20 0.46
KMT2A Q03164 6/20 0.46
KDM4E B2RXH2 5/20 0.46
MEN1 O00255 4/20 0.46
NPSR1 Q6W5P4 3/20 0.46
LMNA P02545 3/20 0.46
RAD52 P43351 3/20 0.46
MAPK1 P28482 2/20 0.46
HSP90AA1 P07900 2/20 0.46
RGS12 O14924 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL636735 1.00 SMN1; SMN2 (0.78) SMN1; SMN2NPC1RAB9APOLBHTT
Bromide SCHEMBL27738133 1.00 SMN1; SMN2 (0.78) SMN1; SMN2NPC1RAB9APOLBHTT
SCHEMBL329523 0.98 NPC1 (0.74) SMN1; SMN2NPC1RAB9APOLBHTT
SCHEMBL29561419 0.98 NPC1 (0.74) SMN1; SMN2NPC1RAB9APOLBHTT
Iodide SCHEMBL5763691 0.96 NPC1 (0.71) SMN1; SMN2NPC1RAB9APOLBHTT
Fluoride Ion SCHEMBL29252280 0.96 NPC1 (0.71) SMN1; SMN2NPC1RAB9APOLBHTT
Hydrochloric Acid SCHEMBL30211052 0.96 SMN1; SMN2 (0.71) SMN1; SMN2NPC1RAB9APOLBHTT
Hydrochloric Acid SCHEMBL326785 0.96 SMN1; SMN2 (0.71) SMN1; SMN2NPC1RAB9APOLBHTT
Bromide SCHEMBL9357936 0.94 SMN1; SMN2 (0.81) SMN1; SMN2NPC1RAB9APOLBHTT
Bromide SCHEMBL635435 0.92 SMN1; SMN2 (0.85) SMN1; SMN2NPC1RAB9APOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024261685-A1 HARDENING COMPOSITION BASED ON RENEWABLE RAW MATERIALS ECOPOX GMBH & CO. KG (DE) 2024-12-26 WO disclosed
EP-4480983-A1 CURING COMPOSITION BASED ON RENEWABLE RAW MATERIALS ECOPOX GmbH & Co. KG (DE) 2024-12-25 EP disclosed
US-20230223595-A1 Heterocyclic Electrolyte Additives for Rechargeable Metal Batteries THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2023-07-13 US disclosed