Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30526523 | 1.00 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL30526512 | 1.00 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL31390759 | 0.86 | HDAC6 (0.66) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL31390754 | 0.86 | HDAC6 (0.66) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL30526519 | 0.84 | CA12 (0.57) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL30526510 | 0.84 | CA12 (0.57) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL30526528 | 0.84 | CA12 (0.57) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL19497780 | 0.83 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL22039979 | 0.83 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL22040024 | 0.83 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554124-B | 2- (2-Benzo [ d ] thiazolylamino) acetamides compound and preparation method and application thereof | 深度感知生物信息有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-116554124-A | 2- (2-benzo [ d ] thiazolylamino) acetamides compound and preparation method and application thereof | 暨南大学 | 2023-08-08 | — | — | CN | disclosed |