Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13456613 | 1.00 | KDM4E (0.57) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13138032 | 0.86 | KCNN4 (0.56) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14044085 | 0.84 | KDM4E (0.56) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10858982 | 0.81 | KDM4E (0.53) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26750090 | 0.81 | KDM4E (0.53) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10734242 | 0.81 | KDM4E (0.53) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8012590 | 0.80 | KDM4E (0.65) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13081367 | 0.79 | KDM4E (0.62) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2373412 | 0.79 | KDM4E (0.62) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15130958 | 0.78 | SLC6A2 (0.70) | KDM4ECFTRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600803-A | Macrocyclic urea orexin receptor agonists | 默沙东有限责任公司 | 2023-08-15 | — | — | CN | disclosed |