Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21397423 | 1.00 | HTR2A (0.39) | HTR2AANPEPCHRNB2CHRNA4KDM1A | |
| SCHEMBL30529310 | 1.00 | HTR2A (0.39) | HTR2AANPEPCHRNB2CHRNA4KDM1A | |
| SCHEMBL21397424 | 1.00 | HTR2A (0.39) | HTR2AANPEPCHRNB2CHRNA4KDM1A | |
| Hydrochloric Acid SCHEMBL23023890 | 0.98 | HTR2A (0.38) | HTR2AANPEPCHRNB2CHRNA4KDM1A | |
| Hydrochloric Acid SCHEMBL30529627 | 0.98 | HTR2A (0.38) | HTR2AANPEPCHRNB2CHRNA4KDM1A | |
| Hydrochloric Acid SCHEMBL23023902 | 0.98 | HTR2A (0.38) | HTR2AANPEPCHRNB2CHRNA4KDM1A | |
| Hydrochloric Acid SCHEMBL30529432 | 0.98 | HTR2A (0.38) | HTR2AANPEPCHRNB2CHRNA4KDM1A | |
| SCHEMBL25523410 | 0.82 | HTR2A (0.43) | HTR2A | |
| SCHEMBL22493782 | 0.82 | PTPN11 (0.37) | HTR2A | |
| SCHEMBL21383675 | 0.82 | PTPN11 (0.37) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4506035-A2 | SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| CN-117263942-A | SHP2 phosphatase inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-112166110-B | SHP2 phosphatase inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-08-11 | — | — | CN | disclosed |