Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.51 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29062038 | 1.00 | KMT2A (0.53) | KMT2AMEN1SCN8ASCN10AKCNK3 | |
| SCHEMBL25376167 | 0.92 | KMT2A (0.51) | KMT2AMEN1SCN8ASCN10AKCNK3 | |
| SCHEMBL30530084 | 0.90 | SCN8A (0.52) | SCN8ASCN10A | |
| SCHEMBL20638927 | 0.90 | SCN8A (0.52) | SCN8ASCN10A | |
| SCHEMBL30530113 | 0.90 | SCN8A (0.65) | SCN8ASCN10A | |
| SCHEMBL25374701 | 0.90 | SCN8A (0.65) | SCN8ASCN10A | |
| SCHEMBL25373808 | 0.89 | SCN8A (0.66) | SCN8ASCN10A | |
| SCHEMBL30530070 | 0.89 | SCN8A (0.66) | SCN8ASCN10A | |
| SCHEMBL20644112 | 0.88 | SCN8A (0.66) | SCN8ASCN10A | |
| SCHEMBL31606706 | 0.88 | SCN8A (0.50) | SCN8ASCN10AKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655497-B | Amidine derivative compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2025-06-03 | — | — | CN | disclosed |
| CN-116655497-A | Amidine derivative compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2023-08-29 | — | — | CN | disclosed |