Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 20/20 | 1.00 |
| ▸ | GRIN2B | Q13224 | 20/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20134122 | 1.00 | GRIN1 (1.00) | GRIN1GRIN2BCYP2D6 | |
| SCHEMBL20134107 | 0.90 | GRIN2B (1.00) | GRIN1GRIN2BCYP2D6 | |
| SCHEMBL31008725 | 0.90 | GRIN1 (1.00) | GRIN1GRIN2BCYP2D6 | |
| SCHEMBL20134102 | 0.90 | GRIN1 (1.00) | GRIN1GRIN2BCYP2D6 | |
| SCHEMBL31008666 | 0.89 | GRIN1 (0.80) | GRIN1GRIN2BCYP2D6 | |
| SCHEMBL20129955 | 0.89 | GRIN1 (0.80) | GRIN1GRIN2BCYP2D6 | |
| SCHEMBL20130005 | 0.87 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL20129966 | 0.87 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL20130009 | 0.86 | GRIN2B (1.00) | GRIN1GRIN2B | |
| SCHEMBL20134430 | 0.85 | GRIN1 (0.74) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523311-B1 | SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-07 | — | — | EP | claimed |
| EP-3523311-B1 | SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-07 | — | — | EP | disclosed |