Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.52 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.52 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26660931 | 1.00 | FGFR1 (0.52) | FGFR1FGFR2FGFR3KDM4EMAPT | |
| SCHEMBL4978879 | 0.86 | FGFR1 (0.51) | FGFR1FGFR2FGFR3KDM4EMAPT | |
| SCHEMBL31134083 | 0.86 | FGFR1 (0.51) | FGFR1FGFR2FGFR3KDM4EMAPT | |
| SCHEMBL16711152 | 0.83 | FGFR2 (0.71) | FGFR1FGFR2FGFR3KDM4EMAPT | |
| SCHEMBL31052754 | 0.81 | KDM4E (0.60) | FGFR1FGFR2FGFR3KDM4EMAPT | |
| SCHEMBL252796 | 0.81 | KDM4E (0.60) | FGFR1FGFR2FGFR3KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL29920009 | 0.80 | KDM4E (0.58) | FGFR1FGFR2FGFR3KDM4EMAPT | |
| SCHEMBL18639993 | 0.79 | MAOB (0.58) | FGFR1FGFR2FGFR3KDM4EMAPT | |
| SCHEMBL6702968 | 0.79 | FGFR1 (0.71) | FGFR1FGFR2FGFR3DYRK1AMAOB | |
| SCHEMBL28738120 | 0.77 | SYK (0.51) | FGFR1FGFR2FGFR3KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600801-A | HSD17B13 inhibitors and uses thereof | FL2022-001公司 | 2023-08-15 | — | — | CN | disclosed |