SCHEMBL30537029

CC[C@H](C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)O)C(C)C)C(C)C

nearest known ligand 0.72

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	12/20	0.72

▸	CCKBR	P32239	4/20	0.72

▸	CALCR	P30988	4/20	0.70

▸	C5AR1	P21730	1/20	0.63

▸	HCRTR1	O43613	1/20	0.62

▸	HCRTR2	O43614	1/20	0.62

▸	NPY1R	P25929	1/20	0.62

▸	NPY2R	P49146	1/20	0.62

▸	NPY4R	P50391	1/20	0.62

▸	NPY5R	Q15761	1/20	0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30537032	0.93	CALCR (0.78)	GLP1RCCKBRCALCR
SCHEMBL30767709	0.92	GLP1R (0.61)	GLP1RCCKBRCALCRC5AR1
SCHEMBL31105353	0.92	GLP1R (0.70)	GLP1RCCKBRCALCRC5AR1NPY1R
SCHEMBL30658220	0.91	GLP1R (0.72)	GLP1RCCKBRCALCRC5AR1NPY1R
SCHEMBL30658354	0.91	CALCR (0.79)	GLP1RCCKBRCALCRNPY1RNPY2R
SCHEMBL30567706	0.91	GLP1R (0.70)	GLP1RCCKBRCALCRNPY1RNPY2R
SCHEMBL31182914	0.91	CALCR (0.69)	GLP1RCCKBRCALCRHCRTR1HCRTR2
SCHEMBL29991271	0.90	GLP1R (0.73)	GLP1RCCKBRCALCRC5AR1NPY1R
SCHEMBL31182929	0.90	CALCR (0.72)	GLP1RCCKBRCALCRNPY1RNPY2R
SCHEMBL31182708	0.90	NPY1R (0.71)	GLP1RCCKBRCALCRNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-112759632-B	Preparation method of Sylvestin	昆明龙津药业股份有限公司	2023-08-18	—	—	CN	claimed
CN-112759632-B	Preparation method of Sylvestin	昆明龙津药业股份有限公司	2023-08-18	—	—	CN	disclosed