SCHEMBL3053897

SCHEMBL3053897

OC/C(F)=C/C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3053900 1.00
SCHEMBL333963 0.75
SCHEMBL333964 0.75
SCHEMBL2323549 0.75
SCHEMBL2468283 0.73
SCHEMBL15514273 0.73
SCHEMBL1220503 0.73
SCHEMBL775537 0.73
SCHEMBL15514271 0.73
SCHEMBL2360242 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030232276-A1 Polymers derived from fluoroalkyl norbornenes, fluorinated crotonates, and/or fluorinated allyl alcohols; Diels Alder reaction of a fluorinated crotonate with cyclopentadiene to form said norbornene; photoresists; dielectrics, light guides HONEYWELL INTERNATIONAL INC. 2003-12-18 US claimed
US-11964938-B2 3-phenyl-4-hexynoic acid derivatives as GPR40 agonists CELON PHARMA S.A. (PL) 2024-04-23 US disclosed
EP-3737470-B9 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS Celon Pharma Sa (PL) 2024-03-13 EP disclosed
EP-3737470-B1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS Celon Pharma Sa (PL) 2022-12-14 EP disclosed
EP-3737470-B1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS Celon Pharma Sa (PL) 2022-12-14 EP disclosed
US-20200399198-A1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS CELON PHARMA S.A. (PL) 2020-12-24 US disclosed
WO-2019134984-A1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS CELON PHARMA S.A. (PL) 2019-07-11 WO disclosed
US-20100190687-A1 PYRIMIDINONE DERIVATIVES AND METHODS OF USE THEREOF SCHERING CORPORATION 2010-07-29 US disclosed
US-20030232276-A1 Polymers derived from fluoroalkyl norbornenes, fluorinated crotonates, and/or fluorinated allyl alcohols; Diels Alder reaction of a fluorinated crotonate with cyclopentadiene to form said norbornene; photoresists; dielectrics, light guides HONEYWELL INTERNATIONAL INC. 2003-12-18 US disclosed
EP-0291045-B1 NOVEL CARBOXYLIC ACID ESTERS, METHOD FOR THEIR PRODUCTION AND INSECTICIDES CONTAINING THEM AS AN ACTIVE INGREDIENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-04-21 EP disclosed
US-5004753-A Novel carboxylic acid esters, method for their production and insecticides containing them as active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-04-02 US disclosed
EP-0291045-A2 Novel carboxylic acid esters, method for their production and insecticides containing them as an active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-17 EP disclosed