Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25344184 | 1.00 | AKR1B1 (0.39) | AKR1B1KLKB1KLK1CA12CA1 | |
| SCHEMBL25981509 | 0.93 | AKR1B1 (0.40) | AKR1B1KLKB1KLK1ROS1ALK | |
| SCHEMBL30539550 | 0.92 | AKR1B1 (0.38) | AKR1B1KLKB1KLK1CA12CA1 | |
| SCHEMBL25350193 | 0.92 | AKR1B1 (0.38) | AKR1B1KLKB1KLK1CA12CA1 | |
| SCHEMBL30539580 | 0.92 | AKR1B1 (0.39) | AKR1B1KLKB1KLK1ROS1ALK | |
| SCHEMBL25348067 | 0.92 | AKR1B1 (0.39) | AKR1B1KLKB1KLK1ROS1ALK | |
| SCHEMBL25348040 | 0.91 | AKR1B1 (0.38) | AKR1B1KLKB1KLK1ROS1ALK | |
| SCHEMBL30539654 | 0.91 | AKR1B1 (0.38) | AKR1B1KLKB1KLK1ROS1ALK | |
| SCHEMBL25990243 | 0.91 | AKR1B1 (0.38) | AKR1B1KLKB1KLK1ROS1ALK | |
| SCHEMBL25345925 | 0.90 | AKR1B1 (0.38) | AKR1B1KLKB1KLK1ROS1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479388-A1 | ANTIVIRAL NAPHTHYRIDINONE COMPOUNDS | Gilead Sciences, Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023154905-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-08-17 | — | — | WO | disclosed |