Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690674 | 0.86 | EPHX2 (0.55) | SLC6A2SLC6A4PARP10EPHX2PARP1 | |
| SCHEMBL1110964 | 0.84 | HTT (0.50) | EPHX2BRAFMAPK1IDO1TDO2 | |
| SCHEMBL10976475 | 0.84 | EPHX2 (0.45) | EPHX2BRAFMAPK1KCNN4IDO1 | |
| SCHEMBL3641624 | 0.83 | APP (0.50) | SLC6A2SLC6A4PARP1MAPK1 | |
| SCHEMBL12970641 | 0.83 | SLC6A2 (0.46) | SLC6A2SLC6A4PARP10EPHX2PARP1 | |
| SCHEMBL30975811 | 0.83 | EPHX2 (0.47) | EPHX2BRAFKCNN4IDO1TDO2 | |
| SCHEMBL2796916 | 0.83 | EPHX2 (0.47) | EPHX2BRAFKCNN4IDO1TDO2 | |
| SCHEMBL1791812 | 0.83 | EPHX2 (0.44) | EPHX2BRAFMAPK1KCNN4IDO1 | |
| SCHEMBL3784022 | 0.83 | SLC6A2 (0.46) | SLC6A2SLC6A4PARP10EPHX2PARP1 | |
| SCHEMBL12291294 | 0.82 | EPHX2 (0.38) | SLC6A2SLC6A4PARP10EPHX2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710434-A | Modulators of MAS-related G protein receptor X2 and related products and uses thereof | 伊赛恩特制药公司 | 2023-09-05 | — | — | CN | disclosed |