Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26613371 | 1.00 | ESR1 (0.45) | ESR1ESR2HTR2CHTR2AMEN1 | |
| SCHEMBL26613451 | 0.89 | ESR1 (0.55) | ESR1ESR2HTR2CHTR2AMEN1 | |
| SCHEMBL29746348 | 0.82 | ESR1 (0.50) | ESR1ESR2MEN1KMT2ANPC1 | |
| SCHEMBL26613515 | 0.82 | ESR1 (0.50) | ESR1ESR2MEN1KMT2ANPC1 | |
| SCHEMBL26613394 | 0.82 | ESR1 (0.50) | ESR1ESR2MEN1KMT2ANPC1 | |
| SCHEMBL28462603 | 0.82 | ESR1 (0.50) | ESR1ESR2MEN1KMT2ANPC1 | |
| SCHEMBL26613543 | 0.81 | ESR1 (0.43) | ESR1ESR2HTR2CHTR2AMEN1 | |
| SCHEMBL29746266 | 0.81 | ESR1 (0.43) | ESR1ESR2HTR2CHTR2AMEN1 | |
| SCHEMBL13784817 | 0.81 | ESR1 (0.51) | ESR1ESR2MEN1KMT2ANPC1 | |
| SCHEMBL30124970 | 0.81 | ESR1 (0.51) | ESR1ESR2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403554-A | Therapeutic or prophylactic agent for amyotrophic lateral sclerosis | 东丽株式会社 | 2025-02-07 | — | — | CN | disclosed |
| CN-116648245-A | Tetrahydroquinoline derivative and medical application thereof | 东丽株式会社 | 2023-08-25 | — | — | CN | disclosed |