Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT7 | O95251 | 20/20 | 0.60 |
| ▸ | KAT6A | Q92794 | 20/20 | 0.60 |
| ▸ | KAT6B | Q8WYB5 | 7/20 | 0.57 |
| ▸ | KAT5 | Q92993 | 7/20 | 0.57 |
| ▸ | KAT8 | Q9H7Z6 | 7/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26074586 | 1.00 | KAT7 (0.60) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL26075903 | 0.93 | KAT7 (0.62) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30545679 | 0.93 | KAT7 (0.62) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL26073879 | 0.90 | KAT7 (0.49) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL26075874 | 0.90 | KAT7 (0.59) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL26074573 | 0.89 | KAT7 (0.58) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30545786 | 0.89 | KAT7 (0.58) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30545673 | 0.88 | KAT7 (0.71) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL26075881 | 0.88 | KAT7 (0.71) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL26077194 | 0.88 | KAT7 (0.57) | KAT7KAT6AKAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499609-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| CN-119301096-A | Inhibitors of MYST family lysine acetyltransferase | 伊索斯泰里克斯公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2023192817-A9 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2024-10-03 | — | — | WO | disclosed |
| WO-2023192817-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2023-10-05 | — | — | WO | disclosed |