Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26575173 | 1.00 | BCHE (0.33) | BCHECES1MAOA | |
| SCHEMBL26125886 | 0.82 | BCHE (0.34) | BCHECES1MAOA | |
| SCHEMBL30546103 | 0.78 | PBRM1 (0.36) | — | |
| SCHEMBL2530842 | 0.78 | PBRM1 (0.36) | — | |
| SCHEMBL26123449 | 0.73 | BCHE (0.39) | BCHECES1MAOA | |
| SCHEMBL26122943 | 0.73 | KDM4E (0.36) | — | |
| SCHEMBL30546133 | 0.73 | KDM4E (0.36) | — | |
| SCHEMBL26124805 | 0.72 | MAOB (0.38) | — | |
| SCHEMBL26125017 | 0.72 | KDM4E (0.35) | — | |
| SCHEMBL26124161 | 0.72 | CYP19A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |