Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB2 | P29323 | 2/20 | 0.77 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.72 |
| ▸ | LDLR | P01130 | 3/20 | 0.68 |
| ▸ | KIT | P10721 | 3/20 | 0.68 |
| ▸ | PCSK9 | Q8NBP7 | 3/20 | 0.68 |
| ▸ | RAF1 | P04049 | 2/20 | 0.68 |
| ▸ | HCK | P08631 | 2/20 | 0.67 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.67 |
| ▸ | BTK | Q06187 | 1/20 | 0.67 |
| ▸ | ABL1 | P00519 | 8/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.67 |
| ▸ | BCR | P11274 | 5/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382296 | 1.00 | EPHB2 (0.77) | EPHB2NR2E1LDLRKITPCSK9 | |
| SCHEMBL22065195 | 0.91 | EPHB2 (0.75) | EPHB2NR2E1LDLRKITPCSK9 | |
| SCHEMBL30546654 | 0.91 | EPHB2 (0.74) | EPHB2NR2E1LDLRKITPCSK9 | |
| SCHEMBL16867179 | 0.91 | EPHB2 (0.74) | EPHB2NR2E1LDLRKITPCSK9 | |
| SCHEMBL22024521 | 0.90 | EPHB2 (0.73) | EPHB2NR2E1LDLRKITPCSK9 | |
| SCHEMBL13659898 | 0.89 | NR2E1 (0.77) | EPHB2NR2E1LDLRKITPCSK9 | |
| SCHEMBL20038839 | 0.89 | EPHB2 (0.72) | EPHB2NR2E1LDLRKITPCSK9 | |
| SCHEMBL22024989 | 0.89 | EPHB2 (0.72) | EPHB2NR2E1LDLRKITPCSK9 | |
| SCHEMBL23265017 | 0.88 | EPHB2 (0.71) | EPHB2NR2E1LDLRKITPCSK9 | |
| SCHEMBL20502614 | 0.88 | ABL1 (0.81) | EPHB2NR2E1LDLRKITPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111039932-B | High-yield synthesis method of radatinib | 安徽峆一药业股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-110872279-B | High-yield synthesis method of nilotinib | 安徽峆一药业股份有限公司 | 2023-09-08 | — | — | CN | disclosed |