Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15779087 | 1.00 | ESR2 (0.52) | ESR2NR1H2ABHD6USP30MAPK1 | |
| SCHEMBL38653711 | 0.90 | ESR2 (0.52) | ESR2NR1H2ABHD6USP30MAPK1 | |
| SCHEMBL30666328 | 0.88 | USP30 (0.45) | ESR2NR1H2ABHD6USP30MAPK1 | |
| SCHEMBL24954372 | 0.87 | ESR2 (0.54) | ESR2NR1H2ABHD6MAPK1ADORA1 | |
| SCHEMBL30893061 | 0.87 | ESR2 (0.54) | ESR2NR1H2ABHD6MAPK1ADORA1 | |
| SCHEMBL30032293 | 0.87 | ESR2 (0.54) | ESR2NR1H2MAPK1ADORA1DPP4 | |
| SCHEMBL19949363 | 0.87 | ESR2 (0.54) | ESR2NR1H2MAPK1ADORA1DPP4 | |
| SCHEMBL19667392 | 0.86 | ESR2 (0.56) | ESR2NR1H2ABHD6MAPK1ADORA1 | |
| SCHEMBL17462471 | 0.86 | ESR2 (0.53) | ESR2NR1H2MAPK1ADORA1DPP4 | |
| SCHEMBL17462462 | 0.86 | ESR2 (0.63) | ESR2NR1H2MAPK1ADORA1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507326-A | Compounds as GLP-1R agonists | 拓臻制药公司 | 2023-07-28 | — | — | CN | disclosed |