Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758871 | 1.00 | MAPT (0.51) | MAPTL3MBTL1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL698534 | 0.87 | MAPT (0.48) | MAPTL3MBTL1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL16095685 | 0.87 | MAPT (0.52) | MAPTL3MBTL1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL31638951 | 0.87 | MAPT (0.51) | MAPTL3MBTL1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL8761806 | 0.86 | MAPT (0.47) | MAPTL3MBTL1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL8761770 | 0.85 | MAPT (0.49) | MAPTL3MBTL1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL16476807 | 0.84 | MAPT (0.45) | MAPTL3MBTL1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL14279014 | 0.83 | MAPT (0.57) | MAPTL3MBTL1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL16097056 | 0.82 | MAPT (0.41) | MAPTL3MBTL1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL3268751 | 0.81 | MAPT (0.49) | MAPTL3MBTL1TDP1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137071-A2 | TRIESTER COMPOUNDS AND METHODS OF USE THEREOF | LIFEMINE THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| WO-2025137084-A2 | TRIESTER COMPOUNDS AND METHODS OF USE THEREOF | LIFEMINE THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-116802176-A | Oxindoles and methods of use thereof | 阿利戈斯治疗公司 | 2023-09-22 | — | — | CN | disclosed |