⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764002 | 0.65 | — | — | |
| SCHEMBL8350491 | 0.63 | — | — | |
| SCHEMBL4896144 | 0.63 | — | — | |
| Potassium SCHEMBL6059809 | 0.62 | — | — | |
| SCHEMBL19138479 | 0.60 | — | — | |
| SCHEMBL13217136 | 0.59 | — | — | |
| SCHEMBL16921964 | 0.59 | — | — | |
| SCHEMBL16849208 | 0.59 | — | — | |
| SCHEMBL6764753 | 0.59 | — | — | |
| SCHEMBL30548942 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116802176-A | Oxindoles and methods of use thereof | 阿利戈斯治疗公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116723844-A | Bicyclic pyridazinones as thyroid hormone receptor beta (TR-beta) agonists | 阿利戈斯治疗公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116710443-A | 2-pyridones as thyroid hormone receptor modulators | 阿利戈斯治疗公司 | 2023-09-05 | — | — | CN | disclosed |