Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 20/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25320831 | 1.00 | TIPARP (0.55) | TIPARPHDAC1HDAC6TNKSPARP14 | |
| SCHEMBL25320827 | 1.00 | TIPARP (0.55) | TIPARPHDAC1HDAC6TNKSPARP14 | |
| SCHEMBL25320398 | 0.92 | TIPARP (0.60) | TIPARPHDAC1HDAC6 | |
| SCHEMBL30550598 | 0.92 | TIPARP (0.57) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25320413 | 0.92 | TIPARP (0.57) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25320395 | 0.92 | TIPARP (0.60) | TIPARPHDAC1HDAC6 | |
| SCHEMBL25320418 | 0.92 | TIPARP (0.57) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25321104 | 0.91 | TIPARP (0.58) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25321110 | 0.91 | TIPARP (0.58) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL30550749 | 0.91 | TIPARP (0.58) | TIPARPTNKSPARP14PARP10PARP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024663-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-01-30 | — | — | WO | claimed |
| WO-2025024663-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-01-30 | — | — | WO | disclosed |
| EP-4469448-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |