Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 15/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25903730 | 1.00 | TIPARP (0.50) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25903612 | 1.00 | TIPARP (0.50) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25320275 | 1.00 | TIPARP (0.50) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL30550643 | 0.96 | TIPARP (0.51) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25321625 | 0.96 | TIPARP (0.51) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL30550870 | 0.96 | TIPARP (0.51) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25321033 | 0.96 | TIPARP (0.51) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25907638 | 0.96 | TIPARP (0.51) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL26658866 | 0.95 | TIPARP (0.49) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25904009 | 0.94 | TIPARP (0.52) | TIPARPKITFLT3GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469448-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |