Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 20/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | CBLB | Q13191 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25319770 | 1.00 | TIPARP (0.56) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25319767 | 1.00 | TIPARP (0.56) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25322719 | 0.93 | TIPARP (0.56) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL30550671 | 0.93 | TIPARP (0.56) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25322715 | 0.93 | TIPARP (0.56) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL30550592 | 0.90 | TIPARP (0.62) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25321041 | 0.90 | TIPARP (0.62) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25321036 | 0.90 | TIPARP (0.62) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL26782565 | 0.88 | TIPARP (0.61) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25320748 | 0.88 | TIPARP (0.72) | TIPARPTNKSPARP14PARP10PARP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024663-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-01-30 | — | — | WO | claimed |
| WO-2025024663-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-01-30 | — | — | WO | disclosed |
| EP-4469448-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |