Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.54 |
| ▸ | TNF | P01375 | 5/20 | 0.34 |
| ▸ | SIK1 | P57059 | 1/20 | 0.33 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.33 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25320871 | 1.00 | TIPARP (0.54) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25320875 | 1.00 | TIPARP (0.54) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25322613 | 0.89 | TIPARP (0.49) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL30550829 | 0.89 | TIPARP (0.49) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25322618 | 0.89 | TIPARP (0.49) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL30550877 | 0.88 | TIPARP (0.51) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25324753 | 0.88 | TIPARP (0.51) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25324750 | 0.88 | TIPARP (0.51) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25900544 | 0.88 | TIPARP (0.48) | TIPARPTNFSIK1SIK2SIK3 | |
| SCHEMBL25323234 | 0.87 | TIPARP (0.48) | TIPARPHTR2AHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469448-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118591537-A | PARP7 inhibitors | 吉利德科学公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |