Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 20/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322091 | 1.00 | TIPARP (0.53) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25322085 | 1.00 | TIPARP (0.53) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25319387 | 0.91 | TIPARP (0.56) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25319383 | 0.91 | TIPARP (0.56) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25324377 | 0.90 | TIPARP (0.56) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25324380 | 0.90 | TIPARP (0.56) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25324311 | 0.88 | TIPARP (0.54) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25324315 | 0.88 | TIPARP (0.54) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25321340 | 0.88 | TIPARP (0.53) | TIPARPTNKSPARP14PARP10PARP12 | |
| SCHEMBL25321334 | 0.88 | TIPARP (0.53) | TIPARPTNKSPARP14PARP10PARP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469448-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118591537-A | PARP7 inhibitors | 吉利德科学公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |