Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 1.00 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.66 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244621 | 1.00 | EGFR (1.00) | EGFRABCG2ERBB2ALK | |
| SCHEMBL17124151 | 0.92 | EGFR (0.84) | EGFRABCG2ERBB2 | |
| SCHEMBL4587672 | 0.88 | ALK (0.79) | EGFRABCG2ALK | |
| SCHEMBL18349251 | 0.87 | EGFR (0.77) | EGFRABCG2ERBB2ALK | |
| SCHEMBL1192454 | 0.86 | EGFR (1.00) | EGFRABCG2ALK | |
| SCHEMBL8871973 | 0.86 | EGFR (0.83) | EGFRABCG2ERBB2ALK | |
| SCHEMBL4587413 | 0.86 | EGFR (0.83) | EGFRABCG2ALK | |
| SCHEMBL8871504 | 0.86 | EGFR (0.76) | EGFRABCG2ERBB2ALK | |
| SCHEMBL27940882 | 0.85 | EGFR (0.73) | EGFRABCG2ERBB2 | |
| SCHEMBL8871526 | 0.83 | EGFR (0.71) | EGFRABCG2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529386-A | Therapeutic diagnostic probes and their use for targeting and/or labelling EGFR kinase and/or EGFR family member expressing cells | 天津大学 | 2023-08-01 | — | — | CN | disclosed |