Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 4/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25337250 | 1.00 | PLK1 (0.53) | PLK1SYKCAMK2DSCN9AKCNH2 | |
| SCHEMBL25339219 | 0.92 | PLK1 (0.59) | PLK1SYKSCN9AKCNH2CDK2 | |
| SCHEMBL30554620 | 0.92 | PLK1 (0.59) | PLK1SYKSCN9AKCNH2CDK2 | |
| SCHEMBL27445382 | 0.84 | PLK1 (0.56) | PLK1CAMK2DSCN9AKCNH2CDK2 | |
| SCHEMBL2946515 | 0.83 | PLK1 (0.77) | PLK1SYKCAMK2DCDK2PIK3CA | |
| SCHEMBL25337631 | 0.83 | PLK1 (0.72) | PLK1SYKCAMK2DSCN9AKCNH2 | |
| SCHEMBL30554478 | 0.83 | PLK1 (0.72) | PLK1SYKCAMK2DSCN9AKCNH2 | |
| SCHEMBL25336685 | 0.83 | IKBKB (0.63) | PLK1SYKCAMK2DSCN9AKCNH2 | |
| SCHEMBL31119043 | 0.83 | IKBKB (0.63) | PLK1SYKCAMK2DSCN9AKCNH2 | |
| SCHEMBL31118851 | 0.81 | PIK3CA (0.55) | PLK1SYKCAMK2DSCN9AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472953-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | Nexys Therapeutics, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| CN-118891251-A | Aryl hydrocarbon receptor agonists and uses thereof | 奈可萨斯医药有限公司 | 2024-11-01 | — | — | CN | disclosed |
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |