Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.68 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.68 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.66 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.66 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.66 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.66 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.66 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.66 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.57 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.57 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17626959 | 1.00 | SMN1; SMN2 (0.68) | SMN1; SMN2NR5A2NR5A1LPAR1LPAR4 | |
| SCHEMBL19821339 | 1.00 | SMN1; SMN2 (0.68) | SMN1; SMN2NR5A2NR5A1LPAR1LPAR4 | |
| SCHEMBL8994530 | 0.94 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1LPAR1LPAR4 | |
| SCHEMBL19065066 | 0.94 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1LPAR1LPAR4 | |
| SCHEMBL9560238 | 0.94 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1LPAR1LPAR4 | |
| SCHEMBL9015289 | 0.94 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1LPAR1LPAR4 | |
| SCHEMBL25336885 | 0.94 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1LPAR1LPAR4 | |
| SCHEMBL11131776 | 0.94 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1LPAR1LPAR4 | |
| Lysophosphatidylcholine SCHEMBL19787878 | 0.94 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1LPAR1LPAR4 | |
| SCHEMBL8530885 | 0.94 | SMN1; SMN2 (0.76) | SMN1; SMN2NR5A2NR5A1LPAR1LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |