Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25364945 | 0.89 | PTGER4 (0.53) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL26783988 | 0.88 | PTGER4 (0.44) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL26784907 | 0.86 | PTGER4 (0.43) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL26034568 | 0.82 | DRD4 (0.44) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL25364058 | 0.80 | CNR2 (0.41) | DRD4ALDH1A1DRD2CNR2CNR1 | |
| SCHEMBL26798680 | 0.80 | DRD4 (0.42) | DRD4KDM4EALDH1A1HTR2ASLC6A5 | |
| SCHEMBL26659866 | 0.76 | PTGER4 (0.41) | PTGER4KDM4ECNR2CNR1 | |
| SCHEMBL1845535 | 0.76 | KDM4E (0.45) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL25365969 | 0.76 | PTGER4 (0.42) | PTGER4DRD4DRD2CNR2CNR1 | |
| SCHEMBL26785109 | 0.76 | PTGER4 (0.42) | PTGER4DRD4DRD2CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158221-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING ANTICANCER AGENT AND NOVEL COMPOUND HAVING INHIBITORY ACTIVITY WITH RESPECT TO PROSTAGLANDIN E2 RECEPTORS | 주식회사 카나프테라퓨틱스 | 2023-08-24 | — | — | WO | disclosed |