Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 16/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550763 | 1.00 | PDE2A (0.66) | PDE2AHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL29685925 | 1.00 | PDE2A (0.66) | PDE2AHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL14120778 | 1.00 | PDE2A (0.66) | PDE2AHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL4233776 | 1.00 | PDE2A (0.66) | PDE2AHTR2AHTR2CHTR2BIDO1 | |
| Hydrochloric Acid SCHEMBL2715888 | 0.98 | PDE2A (0.64) | PDE2AHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL16043553 | 0.87 | PDE2A (0.51) | PDE2A | |
| SCHEMBL16044616 | 0.87 | PDE2A (0.51) | PDE2AHTR2AHTR2CHTR2B | |
| SCHEMBL16868139 | 0.85 | PDE2A (0.50) | PDE2AHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL20811529 | 0.85 | PDE2A (0.67) | PDE2AHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL22221342 | 0.85 | PDE2A (0.67) | PDE2AHTR2AHTR2CHTR2BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112062730-B | 4-oxo-3, 4-dihydro-1, 2, 3-benzotriazines as modulators of GPR139 | 武田药品工业株式会社 | 2023-09-29 | — | — | CN | disclosed |